lpr Mice,MRL

《英文msh词典》lpr Mice,MRL
[入口词] lpr Mice,MRL
[主题词] Mice,Inbred MRL lpr
[英文释义] A mouse substrain that is genetically predisposed to the development of systemic lupus erythematosus-like syndrome,which has been found to be clinically similar to the human disease. It has been determined that this mouse strain carries a mutation in the fas gene. Also,the MRL/lpr is a useful model to study behavioral and cognitive deficits found in autoimmune diseases and the efficacy of immunosuppressive agents.